Fox, now 51, was in his early 20s and the star of the hit TV series "Family Ties" when he took on the role of Marty McFly.
In the film, McFly is accidentally sent back in time from 1985 to 1955, where he meets his future parents in high school. But when he accidentally sparks the romantic interest of his future mother, played by Lea Thompson, he has to work to get his parents to fall in love in order to keep history -- and his future family -- intact. He enlists the help of scientist Dr. Emmett "Doc" Brown to get back to 1985.
Fox went on to star in both "Back to the Future" sequels, released in 1989 and 1990, as well as several films, including "Bright Lights, Big City," "Casualties of War" and "Doc Hollywood," before returning to television in another hit series, "Spin City."
During the series' third season, Fox announced that he had Parkinson's disease and he left the show after the fourth season to spend more time with family.
Since then, he has made guest appearances on several TV shows and written three books while becoming one of the most visible advocates for Parkinson's research. Last August, he signed a deal with NBC to star in a new comedy series based loosely on his life. It's scheduled to air this fall.
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